Sentence examples for have a recurrent mutation from inspiring English sources
A majority of patients with WM have a recurrent mutation of the MYD88 gene (MYD88 L265P).
Therefore, there is evidence that V218 has a recurrent mutation within haplogroup I.
This test locates pairs of closest segregating sites with four haplotypes that could not have arisen without recombination or a recurrent mutation.
Previously, the MYD88 S291C mutation, a recurrent mutation in DLBCL, has been reported in a patient with WM.
All three polymorphisms may have undergone recurrent mutation (or gene conversion) in the past (Stead and Jeffreys 2002), so a given allele at each of these SNPs might be present on very different ancestral lineages.
We have identified a recurrent deleterious mutation in the BRIP1/FANCJ gene in a set of familial and young-onset PrCa cases.
Indeed, deep sequencing efforts have outlined recurrent mutations in a number of epigenetic regulators in AML.
These efforts have detected recurrent mutations in a gene encoding isocitrate dehydrogenase (IDH1) in several tumor types including prostate cancer.
Several recent studies have demonstrated recurrent mutations as a key mechanism by which gene copy number fluctuations take place within short generational time scales [ 49].
bUnrelated probands have the same recurrent mutation (KCNC1 p.Arg320His), demonstrated to be de novo in 9/13.
