Exact(1)
Interestingly, individuals with Cornelia de Lange syndrome do not appear to have a predisposition to develop cancer, but this may be due to the shortened lifespan associated with a severe disease state.
Similar(59)
Children with Down Syndrome (DS) have a predisposition to developing CRLF2 rearranged-ALL which is observed in 60% of DS-ALL patients.
Thus, like other cases of DC and RTS, patients with C16orf57 mutations have a predisposition to developing cancer.
By 18 months after the initial wounding, we observed that 43% of all wounded fish had developed melanoma at the site of wounding while none of the unwounded fish exhibited fin tip melanomas (Fig 1A, B and E), suggesting that chronic wounding can indeed increase the likelihood of cancer growth in tissues that already have a predisposition to developing melanoma.
Current thinking is that some patients have inherited a predisposition to develop thyrotoxic periodic paralysis under the right set of circumstances.
Not surprisingly, neuroticism has been regarded as a predisposition to develop all kinds of psychopathology, including the anxiety disorders [ 1].
Although some of these studies demonstrate a potential protective role for vitamin D in breast cancer, suggesting that disruption of the vitamin D signalling pathway may be a predisposition to develop the disease, others have failed to support a causal relationship between vitamin D intake or supplementation and breast cancer risk.
This is a rare recessive gene disorder that is characterized by shorter height and a predisposition to develop cancer.
Neurofibromatosis 1 (NF2), NF2, and schwannomatosis are characterized by a predisposition to develop multiple neurofibromas and schwannomas.
Aversive stressful experiences are typically associated with increased anxiety and a predisposition to develop mood disorders.
Although their etiology is not well known, several factors have been implicated as representing a predisposition to developing liver abscesses.
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