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Younger patients who develop acute or chronic mesenteric ischaemia usually have a predisposing condition such as vasculitis, collagen vascular disease, hypercoagulable state or vasoactive medications [3].
Gallstones are quite rare in healthy children, but they more frequently occur in subjects who have a predisposing condition [ 1, 2].
Approximately half the children presenting with AIS have a predisposing cause 14 (symptomatic AIS) (fig 3), while the remainder were previously well (cryptogenic AIS); around 80% of both groups have abnormal arterial imaging.
This small sub-group might, then be viewed as 'addicted', but it may also be discovered that the loss of control in this sub-group might have a predisposing condition.
Features of individuals with pulmonary Tb versus NTM are shown in Table 2. Patients with pulmonary Tb were more likely to be reported as immigrants (p < 0.001) and less likely to have a predisposing risk factor (p = 0.002).
This technique focuses on personal relations and role transitions that could have a predisposing and maintaining role in EDs, in order to achieve better social interactions and to cope with interpersonal conflicts [ 41- 43].
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Similar findings have been also described by Wilder-Smith et al. ; of their five PL-IHS patients, three had a predisposing prothrombotic condition.
Eighty-one percent of 225 patients with listeriosis studied in France had a predisposing immunocompromising condition, whose severity was the major prognostic factor [ 17].
Thus, to our knowledge, the synonymous polymorphism c.639C>A (p.Gly213Gly) that we found as having a predisposing effect on CRC (OR 1.24) at the heterozygous (CA) or homozygous state (AA), had not been examined within this context to date and its precise impact on PTGS1 activity would require further functional studies.
Having a predisposing disease more than doubled the risk for complications (RR 2.5, 95% CI 1.2 5.4) but was not clearly associated with being infected with a resistant virus (RR 1.4, 95% CI 0.6 3.2).
Fewer than 4% of the children in the cohort of Journy et al had a predisposing factor and the correspondence percentage for the general population is likely to be lower still, given that children with a predisposing factor may be more likely to receive CT scans than other children.
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