Sentence examples for have a negative role from inspiring English sources
On the other hand, cyclin D1 appears to have a negative role on adipogenesis as Fu et al reported that this cyclin negatively regulates PPARγ-mediated adipocyte differentiation through recruitment of HDACs to the promoter region of PPARγ target genes (Fu et al, 2005).
On the other hand, it has been proven that, in large amounts, these metals can cause oxidative stress in the animal body, which can on the one hand be beneficial, killing tumour cells, but on the other hand it may have a negative role inducing cancer by oxidative DNA lesion [34].
This finding indicates that Src kinases do not have a negative role in the activation of the NF-κB pathway.
Because SOX9 interacts also with genes that are not expressed in chondrocytes but are expressed in a cell type that is derived from a common progenitor, SOX9 could have a negative role in these genes.
The KNAT3 related genes were co-expressed with the down-regulated cellulose synthesis machinery genes, which supports the idea that they have a negative role in TW cellulose biosynthesis.
Since most of the cellulose synthesis genes were up-regulated in TW compared with OW (except POPTR_0002s25970, POPTR_0001s12940, POPTR_0004s11620, and Pt-CESA4.1), KNAT3 may have a negative role in regulating cellulose biosynthesis.
So, the presence of a Mo bond coat as a barrier between the coating and the substrate has a negative role on the adhesion.
The findings of the study revealed that having no role to play in work culture "was more detrimental to one's well-being than having a negative role to play".
Based on the knowledge that IFNγ, has generally been considered having a negative role on Th17 cell differentiation and expansion [35], this direct relation could be due to an individually balanced cytokine pattern.
One possible explanation is that the disruption of ADE2 has a negative role on replicative lifespan.
