Exact(2)
To yield potent inhibitors of beta-amyloid (Abeta) aggregation, we synthesized small molecules that increase their steric bulk by binding to chaperones but also have a moiety available for interaction with Abeta.
The thesaurus takes a battering: Meyer and Brysac will not have half of something if they can have a moiety; they will not give a gift if they can give a lagniappe; they will not quote a saying if they can quote an apothegm.
Similar(58)
?m sio:'has proper part' ?f. #that has a moiety.
These polymerizable dyes have a methacrylate moiety for copolymerization with styrene and suitable spacers between the dye nucleus and the methacrylate function to promote the solubility of the dye.
The latter two have a peptidic moiety bonded near the carboxyl end and one hydroxyl group on the aliphatic chain.
It seems that most of the photoallergic substances have a photohaptenic moiety; promethazine serves as a photohapten because of its photocoupling ability to protein.
The four-ringed heptapeptide scaffolds of UK68597 and ristocetin are also glucosylated at Hpg4, whereas teicoplanin (GtfB) and A40926 (Dbv9) have a GlcNAc moiety at Hpg4.
The Marquis reagent, which reacts with all nitrogen-containing drugs, is negative for cathinones, such as cathinone and mephedrone, but is positive for cathinone analogs that have a methylenedioxy moiety in each molecule.
In this regard, certain GBCAs (i.e. gadobenate dimeglumine, MultiHance; gadoxetic acid, Primovist) have a hydrophobic moiety in their structure, which enables the agent to interact reversibly with serum proteins.
Def1 also contains a ubiquitin-binding domain (UBD), but this domain does not have a ubiquitin-moiety as its primary target.
Also called diimine or diimide, these metabolites have an azo moiety (–N=N–) [1, 2, 3, 4].
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