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In "So Little Time," Mary-Kate and Ashley play Riley and Chloe, respectively, 14-year-old fraternal twins running head-on into typical teenage troubles -- if, perchance, the typical teenage viewer happens to live on Malibu Beach, have a knockout wardrobe and attract constant male attention.
Happily, the movies on the new "Marx Brothers Silver Screen Collection" (Universal) — the five features that the team made for devil-may-care Paramount before scoring their biggest hits at staid old M-G-M M-G-M M-G-Mockout wit sure to level young initiates.
You might have a knockout idea and a brilliant strategy for executing that idea, but if you can't properly hand the baton over when that item or service is made to scale and commercialized, then you'll lose the innovation race.
However, even in the model system C. elegans, only about 25% of the essential genes have a knockout alleles.
Although the possible splice variation is in frame, it contains two stop codons, indicating that it would have a knockout effect, eliminating the last 20 exons.
For this family, there are mutations in all 21 genes, and several of these only have a knockout allele provided by the Deletion Consortium.
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(George Stephanopoulos has a knockout Q rating).
But we may as well admit Verizon has a knockout network.
But he has a knockout punch and a fist, one player says, "the size of my Uncle Murphy's prostate".
Lexicon has a knockout mouse that lacks the brain cell receptor that Prozac focuses on and that has the predicted behavioral effects.
The "Great Russian" version (often pretty touristy and laden with kitsch, even by "Nutcracker" standards) has a knockout male dancer in the Arabian divertissement, Sergey Chumakov.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com