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This region may have a dosage sensitive gene(s) that plays a role in the development of the genitourinary system in humans.
YSL might enhance the efficacy of doxorubicin and have a dosage sparing effect which can reduce the dosage of doxorubicin to reduce its side-effects.
Therefore, the H3-like genes may be full/partial redundancy to other HTRs or have a dosage dependent manner when forming nucleosome.
Of very important note is that because buprenorphine is a mixed opioid agonist/antagonist, it does have a dosage ceiling [ 38, 39].
For a truly unexposed applicator to be shown to have a dosage statistically similar to zero, this estimated total 4-day excretion with zero exposure must be subtracted from the 4-day collection value.
Furthermore, we consider it useful for the future studies to compare Z-linked gene expression in condor males and females to see if there is any difference or if we have a dosage compensation effect similar to what was shown for the zebra finch and chicken [ 53, 54].
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Sun1 and Sun2 have a dosage-dependent but non-redundant effect on the migration and dendritic morphogenesis of Purkinje cells.
Using the EZ-TAXIScan chemotaxis assay, both compounds were also found to have a dosage-dependent inhibitory effect on murine neutrophil migration.
In this study, we further demonstrate that Sun1 and Sun2 have a dosage-dependent but nonreciprocal effect on the migration and dendritic morphogenesis of Purkinje cells during postnatal cerebellar development.
It was found that 2BP had a dosage dependent inhibitory effect on ALP expression.
However, as a note of caution, it has been reported that the expression of GAL4, which is intrinsic to our model, has a dosage and temperature dependent deleterious effect on the expressing cells [27], [28].
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