In previous works, compounds (2) and (3) have shown to be less active than hyperforin in vitro as inhibitors of synaptosomal serotonin reuptake, but they had a comparable effect as growth inhibitors of P. falciparum cultures, although showing less toxicity [17], [22].
Thus, we excluded a gain-of-function by a simple charge effect as a mechanism, as an acidic residue (glutamate) had a comparable effect as the substitution to a basic residue (lysine and arginine).
When studying activities with higher levels of intensity, music might not have a comparable effect on the exercisers' performance, as when high workloads are undertaken, the exerciser's attention could be shifted towards the painful or fatiguing effects of the exercise [19, 20, 22 24].
This novel role for Na+ ions need not be limited to the acid response, as any local Na+ influx should have a comparable effect.
Severe winter weather conditions are likely to have a comparable effect on major roads, but they will also have comparable or worse effects on minor roads.
For a long while Green seemed to have had a comparable effect on Wallace as she had on the depressed person in his story.
The results of the present study demonstrate, that long term treatment with pamidronate iv has a comparable effect on BMD as oral bisphosphonates.
This suggests, that 9 weeks (∼19 sessions) of progressive RT in GCC patients during BEP had a comparable effect on muscle strength as RT interventions with higher volume (12 52 weeks duration) in other malignancies (Strasser et al, 2013).
In conclusion, our present study demonstrates that treatment during four years with intravenous pamidronate has a comparable effect on change in BMD as treatment with either alendronate or risedronate.
