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LPA has wide-ranging influence on cell physiology and pathophysiology, including increases in cytokine and growth factor expression, alteration of surface-protein trafficking and modulation of transcription [ 103, 104].
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This inhibition system has wide-ranging influences on cognition, behavior, and affect.
The prevalence of CaSR in neocortex indicates that this signaling pathway may have wide-ranging influence on synaptic transmission during normal function and disease states.
Hypovitaminosis D is believed to have wide-ranging influences on vascular physiology, which include both direct (e.g. influences on endothelial cells) and indirect pathways (endocrine, immunomodulatory) [33].
Additionally, like norepinephrine, octopamine acts through multiple receptor-signaling pathways having wide-ranging influences over cellular physiology.
The commander-in-chief also has wide-ranging powers.
This approach has wide-ranging consequences.
Magnani believes that the technique has wide-ranging applications.
The civic engagement gap has wide-ranging repercussions.
However, alcohol has wide-ranging effects on the brain and body.
Headache has wide-ranging adverse effects and is often accompanied by considerable worry [ 1].
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