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Liver biopsy is presently the best means of diagnosing cirrhosis, but it carries a significant risk and has well recognised limitations such as sampling error.
Gestational Diabetes Mellitus (GDM) has well recognised adverse health implications for the mother and her newborn that are both short and long term.
Studies that estimate the financial value of ES facilitate the appreciation of services in widely understood terms, but this approach has well recognised limitations including the fact that financial values under-represent benefits to the poor as they have less capacity to pay than rich people.
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Diet and activity data were self reported (in response to questionnaires), which despite our validation studies, have well recognised limitations.
For example, whooping cough, bronchiolitis, croup, and cough associated with tracheo-oesophageal fistula have well recognised specific features.
A contrary view argued that epidemiologists and occupational health practitioners have well recognised ethical obligations to strive for full professional independence in research [ 21].
Several compounds have been identified in plants which have well recognised antioxidant properties, such as carotenoids, ascorbic acid, α-tocopherol and flavonoids (Block et al, 1992; Hertog et al, 1992) and inhibit cancer development.
Existing data sources, such as incident reporting systems [ 38] and routinely collected hospital episode data [ 39] have well recognised limitations and do not provide a complete set of important outcomes, whilst documentation within medical records is often suboptimal.
This technique, although widely used, has well-recognised flaws.
Finally, the screening process was linked to the partograph, which has well-recognised limitations.
1 Although a key part of national and international health regulations, this system has well-recognised problems including delays in reporting and difficulty in identifying unusual activity.
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