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Boldness is something we expect of novelists, and Keneally has usually demonstrated his by taking on large, complex subjects from the past, the great white whales of history, like the American Civil War (in "Confederates"); the origins of his unruly homeland, Australia (in "The Playmaker"); and the Holocaust (in "Schindler's List," which seems destined to remain his most famous book).
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Pig models have usually demonstrated good predictive value in subsequent clinical trials [4], [5], [8], [11], although current data shows better predictivity for safety than for efficacy assessments.
They have usually demonstrated that cataract operations are effective.
Experiments in rodent islets where TCF7L2 activity has been disrupted have usually demonstrated impaired GSIS (11, 29, 30).
HDAC1 inhibition by MS-275 in vitro has usually been demonstrated using recombinant HDAC1 enzymes (Hu et al, 2003).
RRL was first and has usually been demonstrated through restriction site-associated DNA (RAD) tagging and NGS of RAD tags [ 18, 19].
The neo-expression of gangliosides has been usually demonstrated in a variety of cancers - especially in neuroectoderm-derivated tumours, in which they play a key role in invasion and metastasis.
This two-locus hypothesis is more probable than the single-locus one, because postzygotic incompatibilities have usually been demonstrated to be caused by epistatic interactions between at least two genes.
That approach has usually failed.
Studies that have combined ketamine with morphine in an intravenous Patient Controlled Analgesia (PCA) pump have usually failed to demonstrate a reduction in morphine consumption [ 45- 48].
Moreover, if in doubt, we have usually asked officials to demonstrate the danger of publication and in a minority of cases accepted their argument.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com