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Thus, even though TLR4 is highly conserved from Drosophila to man, the region upstream of the proximal TLR4 promoter has undergone substantial evolution in the mammalian lineage.
Although its mission has remained mostly unchanged, the NPS has undergone substantial evolution in management philosophy since 1916.
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In contrast to other lower teeth, the P3 seems to have undergone substantial evolution within the crown group, largely via the addition of several lophate structures.
The large number of AGO genes suggests that the smRNA regulatory pathways in plants has undergone substantial diversification and evolution.
PAGE A12 Hints That Brain Is Evolving Two genes involved in determining the size of the human brain have undergone substantial evolution in the last 60,000 years, researchers say, suggesting that the brain itself is still undergoing rapid evolution.
It is shown that the intron distribution pattern of neuroserpin gene orthologs has undergone substantial rearrangements during metazoan evolution.
The 4q subtelomere has undergone substantial genomic changes during evolution that have had an impact on chromatin condensation and the region's transcriptional regulation.
They have also been keen not to reveal the tool until it has undergone substantial testing by staff.
The city of San Francisco, for instance, has undergone substantial racial resegregation since retooling its diversity plan to emphasize socioeconomic factors.
In each of these areas the court's conception of the Constitution has undergone substantial changes.
But since then the chat show landscape has undergone substantial changes.
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