Conclusion: Neocartilage created from chondrocytes that have undergone serial passages in monolayer culture exhibited decreased matrix S-GAG and type II collagen, indicative of cellular dedifferentiation.
Of 178 patients diagnosed histologically as having NAFLD, 39 had undergone serial liver biopsies.
The Drosophila STE24 function has a demonstrated role in the male germline, and it appears to have undergone serial duplications in the genome.
We retrospectively compared clinical features with the histological changes in the livers of Japanese patients with NAFLD who had undergone serial liver biopsies.
Pelliccia et al 18 reported on 81 athletes with deeply inverted T waves with no apparent cardiac disease, who had undergone serial clinical, ECG and echocardiographic studies for 9 ± 7 years (range 1 27).
The goal of this study was to examine whether metabolic abnormalities are responsible for the histological changes observed in Japanese patients with nonalcoholic fatty liver disease (NAFLD) who have undergone serial liver biopsies.
From a database of 12 550 athletes, Pelliccia et al 9 reported on 81 athletes with diffusely distributed and deeply inverted T-waves who had no apparent cardiac disease and who had undergone serial clinical, ECG and echocardiographic studies for a mean (SD) of 9 ± 7 years (range 1 27).
For the present retrospective analysis, we identified 55 preterm infants of birth weight < 1,500 g who had undergone serial lung function testing (LFT) at three time points (at about 50, 70, and 100 weeks of postmenstrual age) in our outpatient lung function laboratory.
Using non-contrast-enhanced MRI, which yields an incomplete view of synovitis, Hill and colleagues [ 23] reported that change in synovitis on MRI was positively correlated with change in severity of knee pain in 270 persons with symptomatic knee OA who had undergone serial MRIs.
This cloned RH-ERP strain has likely undergone laboratory adaptation due to extensive in vitro lab passage, unlike RH-JSR, a non-cloned RH isolate that was propagated in mice and has undergone little serial passage in culture [ 15].
