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Since then, the world has undergone profound changes.
In the six and a half decades since Elizabeth II's coronation, the UK has undergone profound changes.
Moreover, while the luxury goods companies have hunkered down to weather the crisis over the last three years, retail marketing has undergone profound changes.
In the last century this country has undergone profound changes, both in social structure and, more impressively, in the variety of its members' heritage.
This famously scenic coastline from Mendocino north to Fort Bragg -- Caspar being the fleeting speck between them on Highway 1 -- has undergone profound changes in recent years, with tourists displacing timber as the economic mainstay.
But in the past three decades, the neighborhood has undergone profound changes, with the Upper East Side inching northward, immigrants moving in, and good Latin restaurants being complemented by a variety of other types of cuisine.
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But Gold Country has undergone profound change.
Nike has undergone profound change, helping to lead the way on sustainable design and materials.
Examined during the past 20 years, it is apparent that the dialysis system in the United States has undergone profound change, whereas the system in Canada is relatively stagnant.
Le Guin won a national book award for The Farthest Shore in 1973, and on Wednesday reflected on the industry, which has undergone profound change in the more than four decades between these literary achievements.
The huge overhang of bad debts in the banking system, excess industrial capacity and unproductive labour that held back the Japanese economy for over a decade has now largely been cleared.Crucially, much of the corporate sector has undergone profound change.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com