AhpC/AhpD may be important in isoniazid-resistant strains where the catalase-peroxidase KatG has undergone mutation to provide a resistant phenotype [65].
Our comparative analyses of the snoRNAs in gas5 of vertebrates indicted that the mammalian U77 snoRNA might evolve from the other non-mammalian vertebrate cognate U80 snoRNA which has undergone mutation and lost the function of guiding adenine methylation at the corresponding site of 28S rRNA.
It's not the first time pastries have undergone mutations in recent history.
Enzymes in parenthesis have undergone mutations and lack activity.
Embryo-lethal alleles have undergone mutations in the protein-encoding domain of the gene, including deletions and point mutations of conserved residues.
A broad sequencing study has yielded hints that the culprit, called the Chikungunya virus, may recently have undergone mutations that have made it more adept at causing infections.
Pseudogenes derived from LIN28 have undergone mutations and no longer maintain an exact sequence identity to the LIN28 gene.
From this, it can be inferred that original REP sequences flanking the RAYT genes have undergone mutations into another REP variants and were subsequently multiplicated, leading to the presence of both classes from the same REP orthogroup in host genomes.
It is tempting to speculate that some of the polymorphic microsatellites discovered in this study are those that have undergone mutations at some point of time during microbe evolution, perhaps during speciation, and thereafter remained frozen as the 'molecular fossils'.
Among all gene pairs, 0 (0 vs. 0), 34 (7 vs. 27), 8 (4 vs. 4), 7 (5 vs. 2) and 6 (6 vs. 0) pairs had Ka/ Ks ratio approximately equal to 1 for TNLs vs. non-TNLs in strawberry, apple, pear, peach and mei, respectively, indicating that these genes might have undergone mutations causing nonfunctionalization or pseudogenization.
First, because resistance adaptations result from sequence mutation, these ancestral sequences were screened to identify residues that had undergone mutation as HCV evolved along the main trunk of the tree.
