Altogether, genes from the ppa007577m clade seem to have undergone a functional diversification, playing roles in distinct biological processes.
Therefore, plant PHO1 genes have undergone a functional diversification and acquired diverse roles beyond Pi transport and homeostasis.
Such functional analyses will be necessary to reconstruct whether ancestral latrotoxins have undergone a functional shift from arthropod to vertebrate specificity or vice versa.
The authors also show that this family has been transferred to certain bacteria where they infer that it is likely to have undergone a functional shift to participate in B12 salvage.
We did not identify any of these replicated coexpression relationships in the untreated tumor samples as evidence that the residual tumor cells have undergone a functional reorganization during adaptation to tolerate the presence of the drug.
Our results confirm that IPSCs display mitochondria very similar to their natural ESC counterparts, but that after redifferentiation the mitochondrial complement has undergone a dramatic functional improvement compared to both IPSCs and parental fibroblast lines.
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