Sentence examples for has typically been based from inspiring English sources

Because head-to-head comparisons of AEDs (used in the European Union to approve drugs for monotherapy) have not shown substantial differences in efficacy between drugs, FDA approval for use of an AED as monotherapy has typically been based on trials with novel designs that have been criticised for reasons of ethics and clinical relevance.

The prognostic power has typically been based on total RKIP expression and has not considered the significance of phospho-RKIP.

However, the prognostic power has typically been based on total MEK5 expression and does not consider pMEK5.

Determination of a ≥50% threshold for response has typically been based on previous data from patients with FI and on the assumption that this cutoff is clinically meaningful for patients.

Current diagnostic reimbursement policies in the US and many EU countries do not necessarily support the development of high-value molecular tests, as reimbursement of these tests has typically been based on cost, not on value (or potential) value [ 20].

Multi-item questionnaires have typically been based on one of four underlying conceptualizations of addiction or craving (obsessive compulsive, approach-avoidance, multi-dimensional, intensity frequency duration).

Until recently, crowd-animation algorithms have typically been based on some form of flocking activity, in which each character moves in a particular way depending upon how its neighbors move.

In the past estimates have typically been based on conservative treatments of the accident sequence, necessitated by the limited validation status of models used for the phenomena that control the reactor accident evolution.

The method disregarded the local telephone companies' investments in physical networks, on which their rates as regulated monopolies had typically been based, and instead instructed the states to set rates based on "forward-looking" costs, the theoretical and considerably lower costs of replacing the networks with new technology.

Conventional graphene patterning methods have typically been based on top-down processes to achieve well-defined nanoscale patterns.

As a result, suppositions about the presence of house paints in artworks have typically been based on a combination of visual characteristics, anecdotal and historical references.