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HMGB1 has two functional roles, an intra-nuclear function where it positively regulates transcription by affecting chromatin structure [ 51], and an intracellular role (demonstrated in human models) where it can stimulate the inflammatory process by stimulating cytokines from endothelial cells, monocytes and macrophages [ 52- 54].
Coppi, A. et al. The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host.
The luminescent metal ion inside the nanospheres has two functional entities which allow optimizing their luminescence and aqueous solubility separately.
Histone deacetylase 6 (HDAC6) is a member of the class II HDAC family and has two functional deacetylase domains (Valenzuela-Fernandez et al., 2008).
The device has two functional profiles, defined via the object property ba:deviceProfile and corresponding individuals of the concept ba:FunctionalProfile, of which sp FP_58_21502_4_1_11_465 represents the light controller profile from Figure 3.
Once elected, a president has two "functional" years before campaigning for a second term becomes a distraction.
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The Gene Ontology (GO) functional classification [ 27] has three functional categories, i.e., biological process, molecular function and cellular component.
(Navteq has five "functional classes" of road, ranked according to connectivity and speed. An interstate highway is a one; a local street is a five).
PowerNap has three functional components: Initialization, Data Transmission Module, and Dynamic Rescheduling.
Since the C T has eight functional units, it is capable of simultaneously executing up to eight instructions.
The Nexus one has four functional touch buttons at the bottom of the screen (back, menu, home, search) and a navigation trackball pointing device.
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