Thus, it is of paramount importance to clearly define in the VMP what has to be validated, the extent of validation required for each facility / system / equipment / analytical method, the actions to be taken in case of a significant change (e.g. the replacement of a production / quality control instrument with a different one) together with the conditions for re-validation / re-qualification.
The value of miQ as a PCa biomarker has to be validated in independent multicenter validation studies.
The choice of a particular standard-setting method ultimately is an empirical decision, since, as Kane has emphasised [ 27], standards which are set have to be valid, in the same sense that the content of the exams on which they are set also has to be validated.
A PRO is not valid per se, but has to be validated in the context of interest.
Each signature collected has to be validated by the local commune.
"The Palestinian narrative has to be validated for them to feel that they're not constantly treated like second-class human beings outside the domain of human as well as moral and legal consideration.
The chain of routing has to be validated through an analysis of the documentation.
Obviously, the mechanism of adsorption has to be validated by comparing the likely kinetic models.
However, to be a predictor of disease, a biomarker has to be validated.
However, despite promising results in healthy volunteers, this technique still has to be validated in this indication.
In brief, the research study has to be validated with a larger sample size to represent the Malaysian population.
