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A bioidentical hormone that has the same potency as a pharmaceutical manufacturer's hormone would, in all likelihood, have the same risks and benefits of the pharmaceutical hormone.
In the present study we wanted to understand whether VCN: 1. retains the ability of native CN to signal via integrins agonistically in serum-starved non-migratory suspended cells receiving no external input other than disintegrins, and 2. has the same potency as CN by evoking this downstream signal in a dose-dependent manner.
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No appeals to European solidarity or the rights of man have the same potency as a call to defend national borders.
The image of a rotund, washed-up journalist hacking celebrity's phones for News International doesn't have the same potency as the hooded, indoorsy miscreant, neither for headline- nor Hollywood writers.
Among the compounds assayed, 3- 3-pyridyl -3-[4-[2- 5,6,7,8-tetrahydro[1,8]naphthyridin-2-yl)ethyl]indol-1-yl]propionic acid 21 showed the most promising activity on αvβ3- 3-pyridyl -3-[4-[2- 5,6,7,8-tetrahydro[1,8]naphthyridin-2-ylr current leads 3- 3-pyridyl -3-[4-[2- 5,6,7,8-tetrahydro[1,8]naphthyridin-2-yl
Cuspmimab was selected to have the same potency as mehmimab, but with slightly higher maximal absolute difference from placebo value of 58.8%.
While epidemiology studies have shown that plant-based diets help lower the risk of many diseases, synthetic supplements of vitamins and phytochemicals often do not have the same potency as complex plant materials.
Estrogens that have been used in oral contraceptives include estranol, which has about the same potency as estradiol, and mestranol, which is less potent.
The 2-furanyl derivative (13) with an IC50 at 249 nM has about the same potency as 3.
But will they have the same potency in repeats?
Sceptics often predicted that these diplomatic achievements would never make it into the real world; John Major, a British prime minister, once said that the pledge to create the euro had about the same potency as a rain-dance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com