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The multiple daily dosing not only has the issues with fluctuation of plasma drug concentration but may also lead to poor patients' adherence.
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So has the issue of quality victories.
Nor has the issue of corruption helped Labour.
So why has the issue become such a live one?
"She already has the issue of Benghazi, which was diplomatic.
So, too, has the issue's political salience.
How have the issues changed?
We simply did not have the issues here.
"We have the issue of sanctions.
We also have the issue of methane.
Answer: Having the issue every which way.
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