Sentence examples for has substantial limitations from inspiring English sources

While each contributing data source has substantial limitations, we believe that these can be substantially mitigated by the KB development approach that we propose.

Conventional radionuclide perfusion scintigraphy has been used to assess these abnormalities, but it has substantial limitations with respect to spatial and temporal resolution.

Although this approach has been seen as a major step in the expansion of personalized medicine, it has substantial limitations including its high cost and the presence of serious adverse effects.

While these results, and those from a recent trial in rural Kenya [52], are encouraging, this study has substantial limitations.

This method has substantial limitations since the manufacturing capacity is restricted by the availability of eggs, which may be insufficient to meet the urgent requirements for vaccine during a pandemic [1], [2].

However, the clinical use of this particle in diabetic HNF-1α mutation carriers for metabolic control has substantial limitations.

In Toyota Motor Manufacturing Inc. v. Williams, No. 00-1089, the court ruled unanimously that to qualify as disabled, a person must have substantial limitations on abilities that are "central to daily life," not only to life in the workplace.

Moreover, many interventions have substantial limitations (Miller 1999).

Current pharmacovigilance systems still have substantial limitations, however.

The two techniques perform comparably well, yet they both have substantial limitations.

But these studies had "substantial limitations," says psychiatrist Richard Shelton of Vanderbilt University in Nashville, Tennessee, such as small sample sizes or unreliable methods for rating depression.