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An elegant triple labeling PET experiment in schizophrenia or schizoaffective disorder patients has subsequently demonstrated that aripiprazole differentially occupies D2Rs, 5-HT1ARs, and 5-HT2ARs [ 78].
Although HPV vaccination was first approved for use in females, the quadrivalent vaccine has subsequently demonstrated efficacy in terms of preventing HPV-related disease in males and is approved and recommended for use in males in both the US and Australia for the prevention of anal cancer, anal intraepithelial neoplasia and genital warts.
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Many studies have subsequently demonstrated the benefits of PC in this setting [ 2, 3].
Others have subsequently demonstrated highly improved perinatal outcome following TAC compared with the outcomes in their previous pregnancies [ 3– 5].
We have subsequently demonstrated that similar results can be achieved in a large British district general hospital (Lewis et al, 2002; Barry et al, 2003).
However, we have subsequently demonstrated that siRNA-PKCι knockdown of parental 3D MDCK cysts closely mirrors the level of knockdown of 2D MDCK at 72 h post-transfection.
Both tiotropium + olodaterol 2.5/5 and 5/5 µg have subsequently demonstrated efficacy and acceptable tolerability in large phase III trials investigating the FDCs in the Respimat inhaler [ 16, 18].
Second, Plantinga et al. (2011) have subsequently demonstrated that a very similar macronutrient profile is selected by feral cats in the wild.
We have subsequently demonstrated that oral administration of tranilast (~300 mg/kg) to young mice for 9 weeks significantly reduced fibrotic accumulation by ~30% in the diaphragm muscles of mdx mice.
Researchers have subsequently demonstrated that eradication of H. pylori can cure most cases of peptic ulcer disease, a chronic condition long attributed to noninfectious factors such as stress, diet, smoking, and family history (7, 9, 10 ).
Recently, cDNA microarray studies have become a powerful tool to detect differences in gene expression in different kinds of tumours (Ross et al, 2000), and have subsequently demonstrated that expression profiling can serve as a prognostic tool (Alizadeh et al, 2001; van de Vijver et al, 2002).
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