Exact(14)
It has subsequently been validated using further data from the Case Mix Programme, including external validation among critical care units that joined the programme after the development of the model [ 8] but it has never undergone validation using independently collected data.
However, the two genes added to classifier performance during cross-validation in the training data and the full classifier has subsequently been validated in two additional datasets (manuscript in preparation).
It has subsequently been validated against trials of IPTc [17], [19].
The GC test has subsequently been validated as an independent predictor of metastasis risk [ 14– 16].
The Reynolds Risk Score has subsequently been validated in men, again with improved CV global risk prediction.
Although this hypothesis was initially described in murine systems [ 27], it has subsequently been validated in humans as well [ 25, 30].
Similar(44)
Several elements of these guidelines have subsequently been validated in prospective studies [ 13– 16].
These factors have subsequently been validated independently and have been used as exclusion criteria in some de-escalation trials (Ang et al, 2010; Granata et al, 2012).
These comparative studies have furthermore proposed hypotheses which have subsequently been validated by functional and structural studies [ 19, 20, 25, 26].
Actical accelerometer count thresholds have subsequently been validated using calorimetry to classify time spent sedentary, and in light, moderate, and vigorous intensity physical activity in children [ 36].
A motif based metagenomic survey allowed Kannan et al. to broadly classify ELK sequences into major groups and families and identify novel families such as maltose kinase and bacterial spore kinases [ 1] that have subsequently been validated through structural studies [ 34, 35].
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