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Aside from developmental diseases, accruing research has strongly associated SOX2 with cancer.
Systematic review [19,22,23] has strongly associated intermittent childhood or adolescent sun exposure with a higher risk of melanoma.
SLE not only has strongly associated alleles in the class II region, HLA-DR2 (DRB1*1501) and DR3 (DRB1*0301) [ 14], with ORs of 2 [ 17], but also risk variants in the class III cluster, which encodes genes such as TNF and the complement components C2, C4A and C4B.
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Studies have strongly associated major joint injuries including cruciate ligament damage and meniscal tears with the onset of osteoarthritis [ 31].
Most livestock keepers have strongly associated the disease with bites of tsetse flies followed by Stomoxys and Tabanus species of flies.
In contrast, cervical carcinogenesis has strongly been associated with infections by high-risk human papillomavirus (HPVs).
Similarly, having smoker friends has been strongly associated with cigarette smoking.
The Trump name has become strongly associated with real estate development, and Trump has done an excellent job promoting the idea that he owns properties around the world.
Specifically, rs799348, a functional SNP in UBAC2 which has been strongly associated with BD in the Turkish population, has an OR of 1.0 in our population.
Interestingly, inhibition of these pathways has been shown to lead to a depressive phenotype, while activation has been strongly associated with a decrease in depressive symptoms and improved antidepressant response in both central and peripheral systems26,27,28,29,30.
Iron has been shown to affect protein aggregation associated with various neurodegenerative diseases and aging in C. elegans has been strongly associated with a loss in proteostasis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com