These observations suggest that extracellular intact TeNT has specificity for inhibitory neurotransmission, as shown specifically in "synaptic bouton preparations" of isolated spinal neurons (Shin et al. 2012), while BoNT causes a less specific block of synaptic transmission.
The new substrate, Dabcyl-Pro-Arg-Ala-Ala-Ala-Homophe-Thr-Ser-Pro-Lys FAM -NH2, has specificity constants of 6.3 (±0.3) × 104 M−1 s−1 anDabcyl-Pro-Arg-Ala-Ala-Ala-Homophe-Thr-Ser-Pro-Lys FAM -NH2ely.
In order to determine its potential for clinical diagnosis, real-time RT-PCR was used to examine the HCV RNA levels in plasma from sero-positive and negative subjects, showing that the assay is highly sensitive and has specificity of 100%.
This could be explained by the finding that MOF was present at the promoter also in WSTF KD cells, indicating that WSTF-SNF2h chromatin remodelling has specificity for HATs with H3K9-Ac-activity.
Because their differential expression patterns in response to various stresses and different mechanisms for transcriptional regulation, it is possible that each GmPHD gene has specificity in regulation of stress responses.
The substrate specificity of the nuclease is demonstrated in Figure 1B since only the double stranded form of a PCR product was degraded, indicating that the nuclease has specificity to dsDNA.
FTS has specificity towards Ras and Ras driven inflammatory and fibroblasts cell growth, with the advantage that it does not confer a global growth inhibitory effect on every type of cell [35].
To test whether EGCG has specificity for RIG-I, we used luciferase reporter assays driven by NF-κB promoter elements that are responsive to TLR3, TLR4, TLR9 as well as RIG-I.
The FAs did not alter the basal nor the Dex-induced GRE-mediated transcriptional activity, indicating that the inhibition by FAs has specificity with respect to modulation of NR-mediated functions.
The KDM5 class of JmjC proteins has specificity for H3K4.
α1, 2-fucosidase digests off α1, 2 fucose, to which UEA has specificity towards.
