Many occur in polycistronic clusters, or in imprinted regions, suggesting that they are specifically regulated and in turn have specific regulatory roles in the differential modification of selected target RNAs and in the synthesis of ribosomal proteins (Mattick and Makunin, 2005).
Do you have specific regulatory issues like audits, compliance and privacy?
Some evidence favors natural autoantibodies perhaps having specific regulatory functions in the immune system.
They can have specific regulatory characteristics, for example a coherent FFL effectively filters out rapid fluctuations in the inputs.
Especially for KIF5 proteins, KIF5A was found to have specific regulatory role for GABAARs while KIF5B prefers AMPARs [ 52, 89].
One group of specific T. molitor transcripts (TmL7, TmL8, TmL9) lacked homology in both S1 and S2 subsites and may have specific regulatory functions.
Hence, they may have specific regulatory mechanisms of gene expression (e.g., spliced leader trans-splicing, post-transcriptional regulation, etc).. Furthermore, dinoflagellate spliced-leader (dinoSL) trans-splicing is known to be a common transcription mechanism in nuclear genomes [ 15].
Transcripts of cathepsin L and B with negligible level of expression, like TmL15, TmL8, TmB22 and their cathepsin L orthologs (homologs) mainly from chromosome 7, XP_971868, XP_971975, XP_971752, XP_969833, as well as cathepsin B from chromosome 8, XP_966663, may have specific regulatory roles or are not expressed in the gut and may be an artifact of sequence assembly or tissue contamination.
Although we report results for 152 separate transcription factors, many regulators dimerize with others to form a protein complex (TF) which has its own specific regulatory action.
Each tumor sample may have its own specific regulatory program, and therefore pooling different tumor samples would reduce the ability of REACTIN to detect the differential regulatory programs (presumably because no single program is shared amongst all these samples).
