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Indeed, the outlook has so altered that, with the exception of diseases such as cancer and AIDS, attention has become focused on morbidity rather than mortality, and the emphasis has changed from keeping people alive to keeping them fit.
Problem is, this endless pursuit of unnaturally low rates has so altered the Fed's balance sheet that Mr. Bernanke will be hard-pressed to substantially raise rates to combat inflation once consumer and wholesale prices begin to significantly increase.
Mutilated in a concentration camp, Lene somehow managed to have reparative cosmetic surgery, which has so altered her appearance that she is not easily recognizable as her former self, not even to her husband, a bouncer at Phoenix, with whom she longs to be reunited.
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"We can't count on wild pollinators, because we've so altered the landscape that many are no longer viable," she said.
Cable news, satellite radio, podcasts and the Internet have so altered the media landscape that the regulation as written would have little practical effect.
On a wider scale, he marvels at how the actions of one man have so altered the lives of thousands of people.
The two bridges that straddle the Bosphorus, the passage that splits Istanbul and separates Europe from Asia, are very much at the center of these problems: few other bits of tensile steel have so altered the destiny of a city.
Parks began writing about Italy's railways in 2005 for a Granta magazine story and returned to the subject in 2012, after an energetic spate of Italian rail improvements had so altered his steel-clad "family" that he felt a nostalgic need to preserve what he remembered from earlier years.
After the second world war, it was the turn of the left, and anti-marxists such as Raymond Aron and Jean-François Revel were the exception.By the 1980s, however, the moral and economic shambles of Sovietism, the victory of a centre-minded Socialist party and the growing influence of television in politics had so altered the terms of debate that the left intellectual was pronounced dead.
They ended up being like an Excel spreadsheet whose rows and cells you've so altered and updated that you've forgotten what you were trying to do with the thing.
The City Council must see 'substantial proof" that the rezoning serves the "general welfare," and "that conditions and trends in development in the area have so altered" as to justify a zoning change.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com