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Model C has small estimates of absolute Dxy, HR, and R, yet shows significance in the single-group analysis (p=0.021) and non-significant difference in the two-group comparison (p=0.132 and 0.129 for Cox model and log-rank test).
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Therefore many true nulls may have very small p-values from a t-test only because they have small estimated standard errors.
Jeju Black and Chikso were found to have small estimated effective population sizes (N e ) of only 11 and 7, respectively.
These patients had small estimated B values, indicating that the transition from the α to the β phase occurred below MR4.5.
The number of genes having small FDR estimates (say, less than 0.1) is the basis for assessing the importance of the subtypes.
The variation, for the SD estimate, among the 13 sites demonstrates the need to restrict the size of the study window when potential clusters are being evaluated because locations far from the cluster will have small SD estimates.
Again, most of the included predictors had small effect estimates with wide confidence intervals; the exception was inclusion of an epidemiologist/clinical trials methodologist on the study team, with an OR of 5.7.
Other included predictors had small effect estimates and none were found to have a significant association with the outcome variable at alpha = 0.05.> Table 5 shows univariable logistic regression of predictors on the use of clustering analysis to account for multiple therapists.
To assess whether subtypes are promising or not, t-statistics comparing two distinct phenotype groups (e.g., relapsed/not relapsed) within each subtype are computed for whole genes and the number of genes having small FDR estimates (say, less than 0.1) is calculated based on the P values of the t-statistics.
In addition, the estimate obtained from the moving total model with k = 2 has smaller variance than the estimates obtained from the standard models.
Conceptually, a signal with a wide distribution is expected to have a larger entropy estimate, whereas signals with more narrow distributions have smaller entropy estimates.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com