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ROCK has significant functions in cancer progression and metastasis, rendering it a potential therapeutic target [ 9].
Therefore, the PML protein as well as PML-NBs has significant functions for tumor suppression, especially as associated with p53.
32 Serotonin has significant functions during development, early postnatal life and into adulthood and altered hypothalamic pituitary adrenal activity could derive from any or all of these periods.
We developed a highly interactive user-friendly VCGBrowser, which has significant functions like seamless zooming and real-time searching, for users to search and compare the dynamic information of the different populations in VCGDB.
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The Hippo signal transduction pathway has significant function in organ size control, stem cell self-renewal, cancer inhibition and tissue homeostasis in response to multiple stimuli, including cell density and mechanotransduction [ 17, 25, 26].
Although other important factors (e.g. genetic regulation, signaling roles of amelogenin [39], [40]) have significant functions in enamel development, this study focused on the structural analysis of amelogenin MQP repeats.
WRKY III genes have significant functions in regulating plant development and resistance.
Their log2ratios indicate that they have significant functions in regulating soybean seed development.
Eph RTKs are increasingly understood to have significant functions in disease and development (Zantek et al, 1999).
It is possible that several of the expressed GLUT isoforms have significant functions in this tissue that are distinct from their putative roles as glucose transporters.
Further, we characterized proteins encoded by the genes and predict that a number of them have significant functions in various processes during spermatogenesis and fertilization.
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