Sentence examples for has significant functional implications from inspiring English sources

We believe that the phenotype observed in the paternal deletion of the BclX gene has significant functional implications for the understanding of the role of genomic imprinting in the brain.

Indeed, a shift from CB1R to CB1R CB2R signaling could have significant functional implications.

Hence, we think that one of the biggest challenges of comparative genomics lies in the identification of changes in genome content that had significant functional implications.

The referees agreed that the study is of high quality, and that the results are important because they establish the presence of nucleo-cortico feedback, which is likely to have significant functional implications for certain regions of the cerebellar cortex.

In the long-term, the antibiotic resistance genes could be mobilized and inserted into eukaryotic genomes by horizontal gene transfer, which may have significant functional implications in both prokaryotic and eukaryotic genome evolution.

This model relies on the implicit assumption that most breaks of synteny (disruption of the order of markers, genes or regulatory elements, along a chromosome caused by genome rearrangements) do not have significant functional implications.

These conclusions imply a novel paradigm of how distinct HECT E3s relate to each other and therefore have significant functional implications, as a simple example may indicate: on one hand, these results mean that caution is required to compare functional data for Small HERC and Large HERC subfamily proteins, given that their similarity is due to convergence.

Nevertheless, their presence has important functional implications (see Discussion).

Beyond abundance, the spatial organization of immune cells in relation to cancer cells may also have significant functional and clinical implications.

The objective of this study is to determine whether adults with BSCP have greater adiposity in and around their skeletal muscles than their typically developing (TD) peers as this may have significant functional and cardio-metabolic implications for this patient group.

In this study, we detected misfolded tau in a significant fraction of presynaptic and postsynaptic terminals in AD subjects, which had two significant functional implications: (1) it could impair brain network function; (2) it could represent the anatomical substrate of tau synaptic transmission.