Sentence examples for has significant function from inspiring English sources

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The Hippo signal transduction pathway has significant function in organ size control, stem cell self-renewal, cancer inhibition and tissue homeostasis in response to multiple stimuli, including cell density and mechanotransduction [ 17, 25, 26].

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ROCK has significant functions in cancer progression and metastasis, rendering it a potential therapeutic target [ 9].

Therefore, the PML protein as well as PML-NBs has significant functions for tumor suppression, especially as associated with p53.

32 Serotonin has significant functions during development, early postnatal life and into adulthood and altered hypothalamic pituitary adrenal activity could derive from any or all of these periods.

We developed a highly interactive user-friendly VCGBrowser, which has significant functions like seamless zooming and real-time searching, for users to search and compare the dynamic information of the different populations in VCGDB.

Among these target miRNAs of Lrrc75a-as1, miR-29a-3p has been identified to regulate VSMC calcification by targeting ADAMTS-739, while the miR-24 family members have been reported to have significant function in cardiovascular diseases40.

Comparison of the amino acid sequences of these six members of GmPHD family revealed that the N-terminal regions and C-terminal regions were extremely conserved, indicating that these two parts may have significant function (Fig. 1).

This suggests that some of the transcription factors, like tfbE (and other genes alike), while transcriptionally increased in stationary phase may nevertheless have significant function during exponential growth.

Although other important factors (e.g. genetic regulation, signaling roles of amelogenin [39], [40]) have significant functions in enamel development, this study focused on the structural analysis of amelogenin MQP repeats.

WRKY III genes have significant functions in regulating plant development and resistance.

Their log2ratios indicate that they have significant functions in regulating soybean seed development.

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