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Previous work in yeast has shown that point mutations within or adjacent to conserved COQ5 methyltransferase motifs result in a loss of Coq5 function but not Coq5 steady state levels.
Recent work by Bicknell et al. [ 88, 89] has shown that point mutations in the human ORC1, ORC4, ORC6, CDT1 and CDC6 genes are associated with Meier-Gorlin syndrome, a form of primordial dwarfism, and several of these mutations were determined to interfere with proper pre-RC formation.
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Here, we have shown that pointing and tracing gestures effectively highlight relevant and meaningful symbolic and spatial information, and that language can provide a framework for the kind of information that is learned.
Previous models have shown that point-source release of glutamate is a good model for the release of glutamate through a fusion pore [ 14].
This supports the argument reported by Peden et al. [27] that experience in many countries has shown that demerit points system may not have effective outcomes unless effectively supported by visible enforcement.
On the other hand, previous research has shown that awarding points for correctness tends to lead to consensus building around a dominant speaker's ideas, rather than coconstructed reasoning (James, 2006), which could shorten discussion even more.
Since several studies have shown that point mutations in splice sites, splicing enhancers or silencers, may generate splicing variants for single genes [25] [27], we developed a theoretical model of cis-regulated alternative splicing.This simple model allows us to predict the conditions for the emergence and maintenance of alternative splicing variants for genes expressed in several tissues.
Early studies have shown that point mutation is correlated with GC content [ 13, 22].
(89) Directed mutagenesis of cycloartenol and lanosterol synthases have shown that point mutations in the active site can alter the cyclase product specificity.
In mammals, the PAS has been identified early on from its high degree of conservation [ 4] and studies have shown that point mutations of the consensus sequence AAUAAA decrease or abolish polyadenylation efficiency [ 5].
Like BBC2, C4 has shown that idents can become talking points.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com