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There is no evidence of transmission from poultry to humans, but of course this could change, especially since work so far has shown isolates are genetically heterogeneous and thus adaptation could readily occur.
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Experimentation has shown isolated hyper-homocysteinemia to be atherogenic in cystathionine β-synthetase and apolipoprotein-E double knock-out mice (Wang et al. 2003).
Virulence testing is not performed routinely on D. nodosus isolates retrieved from cattle, but a previous study has shown that isolates from cattle without contact with sheep were all defined as benign by the GG-test [ 2].
Analysis of the microsatellite loci of C. immitis to study the genetic diversity of the fungus has shown that isolates from North America are geographically partitioned.
Our group has shown CA isolated from Terminalia chebula inhibits LPS induced inflammation [ 28], inhibits proliferation of colon cancer cells [ 29].
A previous study using random amplified polymorphic DNA (RAPD) markers has shown that isolated S. sponhemica populations have preserved considerable levels of molecular genetic diversity, presumably because the taxon is long lived (Walisch et al., 2014).
Thus, Comamonas sp. EB172 has shown promising bacterial isolates producing polyhydroxyalkanoates from renewable carbon materials.
Phylogenetic analysis of the polyomavirus VP1 gene has shown that BKV isolates belonged to subtypes I and IV.
Experimental work has shown that some isolates of B. burgdorferi do not disseminate, or slowly disseminate, in mice (30).
Previous work on natural isolates has shown that up to 8% of natural isolates may harbor prions (Halfmann et al. 2012).
This study has shown that TAMs isolated from Ewing's sarcoma are capable of differentiation into mature functional osteoclasts.
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