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Berberine, an isoquinoline alkaloid, has shown inhibitory effects on growth of several tumor cell lines in vitro.
Therefore, here we show that since Phyllanthus has shown inhibitory effects before and during DENV2 infection, it is clear that the plant may be inhibiting viral entry, viral motility in cells or the synthesis of viral polyproteins.
As MMP-Inh-1 has shown inhibitory effects on other collagenases (Odake et al, 1994), one cannot completely rule out that other collagenases are playing a role in the mouse sepsis models.
One study using 10 μM glycitein has shown inhibitory effects on cell growth and induction of apoptosis by reduced Bcl-2/Bax ratio in MCF-7 breast cancer cells [ 10].
There are several reasons to suspect that metformin may have specific anticarcinogenic properties, as it has shown inhibitory effects in preclinical models of a number of different tumor types, including prostate [ 9, 13], breast [ 6, 10, 12], pancreatic [ 11], lung [ 14] and colon cancers [ 8, 13].
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Citronella oil has shown inhibitory effect on biodegrading and storage-contaminating fungi [ 17].
From published literature, curcumin has showed inhibitory effects in colon cancer cells (Hanif et al, 1997; Chauhan, 2002).
Extracts from a high number of algae have shown inhibitory effects on other algae, and this is often seen in connection with unsaturated fatty acids (Ikawa, 2004).
Some recent published studies have shown inhibitory effect of calcium phosphate coatings on osteoblasts in vitro [ 50, 51], but their performance in vivo cannot be completely predicted by these data.
Sprouty, on the other hand, has reportedly shown inhibitory effects on other types of sarcoma cells and tumors.
It has shown significant inhibitory effects on inflammation induced by lipopolysaccharide (LPS) in bone-marrow-derived dendritic cells [ 7], primarily by inhibiting chemokine recruitment of macrophages via the Mitogen Activated Protein Kinase (MAPK) cell signalling pathway.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com