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Due to its high selectivity towards Bcr Abl kinase, it has shown high efficacy and mild side effects in patients and has been listed as essential medicines by World Health Organization [34].
In phase II trials, pemetrexed has shown high efficacy and favorable toxicity when given in combination with platinum agents, gemcitabine and vinorelbine [ 12, 13].
Problem-solving skill training is a brief intervention which has shown high efficacy in several diseases both in patients [ 30] and in relatives [ 31].
One of the two vaccines available includes HPV 6 and 11 antigens and has shown high efficacy against external GWs (Garland et al, 2007).
It is a cost-effective procedure for the intervention in advanced knee OA, and has shown high efficacy in relieving pain and increasing mobility.
Rifabutin has shown high efficacy in treating Helicobacter pylori infection, which is associated with a range of upper gastrointestinal diseases including gastric cancer [ 62].
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In the MOSAIC study, the combination of 5FU+FA combined with oxaliplatin has shown higher efficacy than 5FU+FA alone, with a 5.3% reduction of the probability of recurrence at 3 years (Andrè et al, 2004).
Levamisole has showed high efficacy and broad antiparasitic spectrum.
Medical abortion regimens based on the use of either misoprostol alone or in association with mifepristone have shown high efficacy and excellent safety profile in early pregnancy abortion.
The currently licensed rotavirus vaccines have shown high efficacy rates in trials and have focused on the role of the major G genotypes, but the role of P genotypes has not been addressed clearly (3, 4 ).
While recognising the limitations of the still moderate (5 6 years) follow-up in a few tens of thousand young women, two vaccines to date have shown high efficacy, safety, immunogenicity, long-term duration of protection and a strong suggestions of induction of immune memory (Harper et al, 2006; Garland et al, 2007; Paavonen et al, 2007; The Future II Study Group, 2007).
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has shown excellent efficacy
has shown high accumulation
has shown consistent efficacy
has shown high selectivity
has shown high separation
has shown high accuracy
has shown clinical efficacy
has shown significant efficacy
has shown partial efficacy
has demonstrated high efficacy
has shown substantial efficacy
has shown high sensitivity
has shown high inter-observer
has shown high stability
has shown similar efficacy
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