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In the past few months, the simplified CRISPR RNA-guided Cas9 nuclease has shown broad potential for genome engineering in metazoans.
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It can be processed easily to yield large amounts of epithelial and mesenchymal cells that have shown broad differentiation potential.
Rosette-forming neural stem cells expressing anterior markers of the nervous system, such as Forse1, have shown the broadest differentiation potential [ 35].
In contrast to the previous estimates of small effects, genomic sequencing within Arabidopsis has shown the presence of considerable genetic polymorphism in both the plastidic and mitochondrial genomes suggesting the potential for broad phenotypic consequences (Moison et al., 2010).
American investors have shown the potential of the retirement market.
Other esoteric methods have shown potential, too.
Polls have shown even broader support for legal medical marijuana.
Levamisole has showed high efficacy and broad antiparasitic spectrum.
Broad alliances have shown some successes.
In the 10 years since James Thomson's discovery, scientists have shown that embryonic stem cells have the potential to help create replacement cells for a broad array of tissues and organs, including the heart, liver and pancreas.
CAGE tag and other expression analyses have shown that CpG island promoters display a broad and complex distribution of transcription start sites when compared to non-CpG island promoters [ 33, 34] possibly contributing to the observed inherent bidirectional potential.
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