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This is an antibiotic, which has shown an activity against different strains of MAP "in vitro".
As single-agent, fotemustine has shown an activity ranging from 15.5% to 26% in recurrent MGs [ 7- 9].
CALB immobilized onto silica has shown a good activity and improved recyclability with respect to Novozym 435.
The Louvet trial has shown a better activity profile of the combination of these drugs versus monotherapy, but has failed to demonstrate a clear statistically significant survival advantage.
Bendamustine, a novel alkylating agent that demonstrates a lack of cross-resistance with standard alkylators, has shown a significant activity in a variety of lymphoproliferative diseases, including chronic lymphocytic leukemia and indolent lymphomas.
Especially the double mutation at the two sites has shown a substantially decreased activity in the alkaline range (Figure 4).
The extract has shown a significant antimicrobial activity on all tested bacterial and fungal species.
The extract has shown a significant antimicrobial activity towards all bacterial and fungal species tested.
Also in glioma, GSK-J4 has shown a strong antitumor activity both in vitro and in a mouse xenograft model.
Metronomic administration of cyclophosphamide (CTX) in combination with antiangiogenic drugs has shown a potent preclinical activity [ 9].
Electromyography has shown a spontaneous electrical activity (SEA) at TrPs during electrical silence of adjacent muscle fibers.
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