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During the past decade, the emphasis in the study of the pathogenesis of infectious diseases has shifted from determining the function of the cellular players in the inflammatory response to the mediators that orchestrate this response [ 5].
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Now that the full sequence is known, the emphasis has shifted from sequencing to determining the function of individual genes.
Overtime, the analytical focus of empirical models on the factors determining FDI has shifted from traditional determinants of locational advantages to policy-oriented issues, like exchange rate and openness as well as to the governance and human development areas and lately to liberalization under BITs, BTAs, and RTAs.
As the music industry has shifted from analogue to digital, the words have subtly shifted.
Mercifully, the mood has shifted from the go-go 2000s.
The emphasis has shifted from more freedom to more democracy.
The combat has shifted from the desert to the streets.
The focus has shifted from a tactic to an ideology.
The focus has shifted from cancer treatment to prevention.
Given that a true gold standard is unlikely to emerge, investigations have shifted from trying to determine which technique can best diagnose VAP to which diagnostic strategy leads to improved outcomes, such as morbidity, antimicrobial use, and mortality.
As this shift has occurred, the underlying mechanisms that determine economic behavior have shifted from ones of diminishing to ones of increasing returns.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com