Such fact to a large extent has restricted development-oriented MPC among peasants, which is only 0.096, as shown in Table 2.
Parliament members said a 1994 global trade agreement on intellectual property rights has restricted the development of affordable copycat treatments for poorer countries.
The requirement of good refinement performance at relatively low temperature (⩽720 °C) has restricted the development of inoculant in low pressure casting industry.
The lack of clarity with regard to both the predisposing factors and the precise antigenic targets of the immune response has restricted the development of effective therapeutic approaches [9].
While our limited knowledge of the initiating events of ovarian cancer has restricted the development of models in which the early pathogenic events can be studied, recent advances in the ability to manipulate gene expression in ovarian surface epithelial cells in vitro and in vivo have begun to provide insights into the molecular changes that may contribute to the development of ovarian cancer.
The necessity to use human volunteers as baits in mosquito traps inevitably limits their compactness, consistency, cost and safety, and has restricted the development of sustainable mosquito surveillance systems, especially in resource-limited countries [25].
However, very limited genomic resources are available for P. lactiflora, with only 195 nucleotide sequences deposited in GenBank until 24 January 2014, which has restricted the development of modern breeding technologies.
Despite appearing to be a perfect solution for the open method to support a large database, any type of digestion, and any type of modification, the search speed has restricted the development of this approach because of the large search space.
As a result, despite its pharmacological efficacy and safety, this low bioavailability has restricted the clinical development of CUR [17].
But the solubility and bioavailability of this drug are poor, which has restricted the design and development of dosage forms for efficient and successful therapy.
