Sentence examples for has provided a structural from inspiring English sources

CDK2 has provided a structural paradigm for the CDK family and has been widely exploited for structure-aided CDK inhibitor design.

A 'build' approach involving multimodular cellulosomal segments has provided a structural model of an organized yet conformationally dynamic supramolecular assembly with the potential to form higher order structures.

Study of the molecular architecture of isolated doublets has provided a structural basis for understanding mechanical properties related to the bending of the axoneme, and has also offered insight into the potential role of doublets in the mechanism of dynein activity regulation.

Furthermore, the structural resolution of Bacillus stearothermophilus MutY has provided a structural basis for these variants [Fromme et al., 2004].

This study has provided a structural backbone in mapping the apoptotic mechanisms in all alpha-, gamma- and delta-tocotrienols induced apoptosis in both A549 and U87MG cells (see Additional file 2).

On the one hand, available crystal structures of ABC transporters have provided a structural basis for understanding the mechanisms of coupling ATP hydrolysis in the NBDs with the conformational change of the TMDs that is associated with cross-membrane transport of the substrate.

Recently solved crystal structures of norovirus bound to HBGA have provided a structural basis for identification of potential anti-norovirus drugs and subsequently performed in silico and in vitro drug screens have identified compounds that block norovirus binding and may thereby serve as structural templates for design of therapeutic norovirus inhibitors.

These structures have provided a wealth of understanding of the structural biology of the two classes of immunophilins, and have provided a structural basis for understanding the increasingly expanding role of these fascinating proteins in cellular processes.

To sum up, we may have provided a structural rationale as to why the naturally occurring E5D and S3T mutations would not be expected to significantly alter presentation and recognition of epitope QW9 presented by HLA-B*5801 HLA-B*5801al., 2007).

The crystal structures of a bacterial homologue of GlT (Gltph) in both the IF and OF states have provided a structural framework for understanding the transport mechanism of all GlTs.

Genomics has provided a detailed structural description of the cancer genome.