They have proven sensitivity to change, validity and reliability; unfortunately they are mainly based on subjective issues (like patient's appreciation of pain).
The one-item screening tool (thermometer) has proven good sensitivity and specificity in breast cancer patients [ 48, 49].
The laser Doppler technique has proven high sensitivity for measuring changes in digital skin perfusion in response to a dynamic challenge [ 26].
This assay has been assessed, in a population similar to the population in the presented trial, and has proven a sensitivity and specificity in the Netherlands of 98 100% and 79 85%, even in patients on acid suppressive therapy [ 15– 17].
This assay has been assessed, in a population similar to the population in the presented trial, and has proven a sensitivity and specificity in the Netherlands of 98-100% and 79-85%, even in patients on acid suppressive therapy [ 11, 30, 31].
HPV testing has proven greater sensitivity than cytologic screening (Papanicolaou smears) for detection of cervical precancer (cervical intraepithelial neoplasia grade 3 (CIN3)) and cervical cancer (>CIN3) (2– 6) and greater reliability (7, 8).
The significant difference in the signal readings obtained from carefully prepared training sets of adulterated diesel oil composed of low percentages (5 15%) of kerosene has proven the high sensitivity of the developed sensor.
It has proven to lack sensitivity and specificity in large community-based studies [ 101] and further investigation is required to assess the significance of increases in BNP on repeated measures.
Contrast sensitivity has proven to be an especially sensitive measure of visual function that correlates with real-world performance on vision-oriented tasks (e.g., driving, reading speed, face recognition) [ 89- 91].
The VIA test has proven to have similar sensitivity to that of cytology but lower specificity and positive predictive value when evaluated in clinical research settings [ 14].
