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Affinity maturation of antibodies using phage display has proven to be critical to therapeutic antibody development and typically involves modification of the paratope for increased affinity, improved specificity, enhanced stability or a combination of these traits.
Globally, this study has proven the implication of some compounds present in AESb on the rapid maturation of ovarian follicular cells leading to a precocious puberty onset.
This approach has proven especially powerful in the hematopoietic system, where it has been possible to monitor the generation, expansion, maturation, and migration of primitive erythroid cells, macrophages, and megakaryocytes during embryogenesis at unprecedented resolution.
The Drosophila ovary has proven to be a useful model system for studying the mechanisms by which the processes of oocyte maturation and chromosome segregation interact with or are controlled by the meiotic cell cycle.
Although the maturation and fragmentation of MKs in vivo leads to the generation and release of platelets, this thrombopoietic process has proven extremely difficult to recapitulate in vitro.
This has proven controversial.
"Science has proven it.
He has proven results.
This has proven fraught.
ITER has proven otherwise.
His estimation has proven correct.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com