Sentence examples for has proven difficult to study from inspiring English sources

Appendiceal cancer is a rare disease that has proven difficult to study in prospective trials.

This process has proven difficult to study experimentally, and complete descriptions of how the cell couples surface membrane and intracellular signal transduction proteins to achieve both stable and sensitive intracellular calcium release are still lacking.

About 1percentt of the population is affected by schizophrenia, a severe form of mental illness that has proven difficult to study and treat, according to Russell Margolis, director of the Johns Hopkins Schizophrenia Program.

Although it is a relatively short protein, E6 has proven difficult to study due to the inability of the protein to be isolated in a native, soluble form.

Known about for over a century and still poorly understood, the lag phase has proven difficult to study due to the low density and low metabolic activity of bacteria during this phase.

However, microbial communities have proven difficult to study due to a lack of suitable experimental and computational tools.

We validated our technique by measuring sequence preferences for 28 Saccharomyces cerevisiae transcription factors with a variety of DNA-binding domains, including several that have proven difficult to study by other techniques.

The physical properties of bent-core nematic materials have proven difficult to study, but patterns are emerging regarding their optical and dielectric properties.

The process had proved difficult to study, because natural slabs of sandstone erode over millions of years.

However, they have proved difficult to study via conventional cultivation methods because of their slow proliferation rate and sensitivity to variations in their environments.

However, the processes underlying tissue renewal and the mechanisms that govern their coordination have proved difficult to study in the human gut.