In initial sPMCA and bioassay experiments, obex and retropharyngeal lymph node (RLN) tissues from individual animals were pooled, as both these tissues have proven sensitive in the identification of PrPCWD at various stages of infection [22], [29], [30], [31], [32], [33].
In addition, sequencing of the fission yeast transcriptome has proved sensitive enough to detect widespread transcription in >90% of the genome, including traces of RNAs that are not robustly transcribed or rapidly degraded [ 48], such that very rare isoforms expressed at levels below the detection threshold of tiling arrays can be identified.
This problem-solving test is simple to perform and has proven sensitive to nutritional interventions in infants (40, 41).
The Willatts Infant Planningg Test was chosen because it has proven sensitive to past nutritional interventions in infants (46, 55) and has been successfully used in low-income countries (44, 45) where it has, for example, allowed the detection of differences between groups of infants aged 7 mo after a 2-mo psychosocial intervention (44).
However, when the test has been used to assess whether chronic stress can affect behavioral "despair" and, hence, depression-like behavior, a single session has proven sensitive to evidence increased behavioral immobility in depressed animals [50], [51].
Internal consistency is high and the scale has proven sensitive for detecting clinical changes [ 37].
Parvoviruses are non-pathogenic in humans, but human tumor cell lines have proven sensitive to the lytic activity of H-1PV in vitro.
Men's hair has proved a sensitive issue in international politics, even before Trump's indescribable golden arrangement, referred to by one paper as "Norwegian bunch grass".
As the wrist joint has proved more sensitive to changes in bone erosions than other joint areas in RA [ 33], and bone changes in the wrist joint have been shown to possess predictive value with respect to further radiographic erosive progression [ 14, 34, 35], we found the wrist an important joint area to investigate.
The new technique has proved very sensitive to detect differences in the deformation parameters across conditions.
