Manipulating flow velocity, and concomitantly shear stress, has proven adequate to promote endothelial activation and subsequent plaque formation in animals.
While reliance on the EPR effect for tumor targeting has proven adequate for vascularized tumors in small animal models, the efficiency and specificity of tumor delivery in vivo, particularly in tumors with poor blood supply, has proven challenging.
These electrodes and the used methodology have proved adequate to perform voltammetric measurements and kinetic studies without the need of complementary sophisticated instrumentation.
Although some techniques have proved adequate for relating findings in the test tube to the situation in living organisms, study of the more complex metabolic processes, such as those involved in differentiation and development, may require the elaboration of new experimental approaches.
Consequently quite moderate speakers have proved adequate in prosecution, while no one can be a good counsel for the defence unless he possesses real eloquence.
Some who gave evidence to the Royal Commission into the Operation of the Poor Laws suggested that the existing system had proved adequate and was more adaptable to local needs.
Although conventional microarray analytical procedures have proved adequate in handling M-CGH data, data interpretation using these methods is based on a continuous character model in which gene divergence and gene absence form a spectrum of decreasing gene conservation levels.
The pre-trained convolutional networks have already learnt to generate rich image representations that have proven adequate for image classification and segmentation.
