Sentence examples for has profoundly altered from inspiring English sources

"It has profoundly altered me to the very core of my being," a remorseful Avary said in the courtroom.

From the alphabet to clocks and printing, every major new technology has profoundly altered the way in which humans think.

This change has profoundly altered the culture of City Hall, where the mayor's chief of staff or other aides traditionally serve as the gatekeepers to the mayor.

But the combination of success and the proliferation of literary festivals and media platforms has profoundly altered the even tenor of my mostly isolated days.

There can be little doubt, however, that it was a contributing factor and that recognition of its role has profoundly altered concepts of paleoclimatology.

The AIDS epidemic has profoundly altered the way government responds to health emergencies, galvanizing medical research, speeding the review of new drugs and forcing officials who make health policy to share power with patients and their advocates.

Medical advances have profoundly altered the course of human life.

But a few who have made the change to public transportation say that the gas price increases have profoundly altered how they live.

So what am I supposed to do with it?' " Alonso Salazar told me that Pablo Escobar's legacy had profoundly altered political and social life.

Indeed, I would place it on that short shelf of postwar urban classics, like Jane Jacobs's "Death and Life of Great American Cities," Robert A. Caro's "Power Broker" and William H. Whyte's "City," that have profoundly altered the way we looked at cities, and taught us to appreciate their messy, ad hoc, additive nature.

Overall changes in lifestyle, such as western diet, high hygiene standards and overuse of antibiotics, have profoundly altered our microbiome composition.