Sentence examples for has profound functional implications from inspiring English sources

An important change, which has profound functional implications for steroid activation of the GR, is the loss of the contact between Asn564 and the C11 hydroxyl on dexamethasone.

In a genotype to phenotype perspective, the combined effect from the QTLs has profound functional implications.

Taken together, culture expansion of MSC has profound functional implications - these are hardly reflected by genomic instability but they are associated with highly reproducible DNA-methylation changes which correlate with repressive histone marks.

Our findings could have profound clinical implications.

This seemingly simple biochemical change has profound structural and functional implications.

Taken together, our results demonstrate an intrinsically cohesive modular architecture in the spontaneous brain functional networks, which has profound implications for our understanding of the topological mechanisms underlying the spontaneous human brain activity at a large scale.

That statement has profound moral implications.

This classification has profound surgical implications.

The new multidisciplinary adenocarcinoma classification has profound surgical implications.

Moreover, recent studies have suggested that the cellular heterogeneity has profound biological implications [ 37].

Understanding the functional interaction between novelty and reward has profound implications for understanding how long-term plasticity for novel stimuli is regulated.