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To some extent the misidentifications were to be expected as distinguishing members of the Harveyi clade is known to be a difficult taxonomic task (Sawabe et al., 2007) and the advent of genetic methods with high discriminatory power has previously elucidated misidentifications in a substantial percentage of strains tested [71% (Gomez-Gil et al., 2004) and 18% (Pascual et al., 2009)].
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We have previously elucidated a new paradigm for the metal ion-induced helix helix assembly in the natural γ-carboxyglutamic acid (Gla -containing class of conantokin (con) peptides, typified by con-Gla -containing of class, cof-T[K7Gla], independent of the hydrophobiconantokin
We have previously elucidated a signal transduction mechanism that is critical to the survival and expansion of neural stem cells in vitro and in vivo.
We have previously elucidated the mechanism of intracellular delivery of this peptide and documented an endocytosis-independent process of crossing the plasma membrane mediated by the membrane-translocating motif (MTM), which is based on the signal sequence hydrophobic region (SSHR) derived from Kaposi FGF [51].
We have previously elucidated the role of the influenza hemagglutinin (HA) in aerosol transmissibility [ 7, 10- 17].
We have previously elucidated critical roles of NO and chemokines in the immunosuppressive effect of MSCs, with the co-presence of IFN γ and TNF α, or IL-1 as a requisite.
We have previously elucidated a multi-step bile acid 7α-dehydroxylating pathway in these bacteria that allow them to use primary bile acids as an electron acceptor allowing for increased ATP formation and growth., However, most members of Clostridium cluster XIVa lack the bai operon and thus do not convert CA to DCA, so for most of these microbes, energetic considerations can be ignored.
Its structure in complex with Dig has previously been elucidated (PDB code: 3RA7; 18; Fig. 2 A ).
Further, the association between the number of cigarettes smoked per day and smoking cessation has previously been elucidated; 13 14 19 20 nevertheless, evaluations of the link between reasons behind smoking cessation and precise nicotine dependence are limited.
Toward this goal, a structure of p300 bound to a Lys-CoA bisubstrate HAT inhibitor has been previously elucidated, and the enzyme's catalytic mechanism has been investigated.
The distinct role of TRADD in proliferation and apoptosis through binding with TRAF2 and FADD has been previously elucidated.
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