Sentence examples for has presented considerable challenges from inspiring English sources

Development of these drug device combination products has presented considerable challenges to the device industry because it involves a multi-disciplinary approach that combines conventional device design and manufacturing with the principles of controlled local drug delivery.

This phenomenon has presented considerable challenges in the treatment of uveitis in patients with multisystem diseases, such as Behçet's disease or AS.

The complexity surrounding uveitis, regardless of whether it is associated with a systemic rheumatic disease, has presented considerable challenges to understanding its pathogenesis.

As one of the wettest mines in the world, the Konkola mine has presented considerable engineering challenges.

Fankhauser said: "The past year has also presented considerable challenges for Thomas Cook as we confronted the mistakes that were made following the deaths of Bobby and Christi Shepherd in Corfu nine years ago.

The striking sequence divergence of XSV presented considerable challenges for designing suitable primers for RT-PCR and sequencing.

Unfortunately, identifying related by either convergent or direct evolution CRMs for such a systematic study has presented a considerable challenge.

The characterization of pDC lineage has presented a considerable challenge, as pDC display molecular markers and features of several cell types and can be derived from multiple progenitors.

However, the growing numbers of people with dementia, many of whom have other long-term health conditions, present considerable challenges for primary care.

However, the design of autonomous decision-making systems presents considerable challenges, particularly when they have to achieve their goals within a dynamic context.

While bisectoral care and multidisciplinary care both present considerable challenges, they also hold great potential for optimizing care.